Wound sealant – Mepiseal®
Secure with care
Achieving and maintaining a seal is essential for any negative pressure wound therapy(NPWT) treatment. Mepiseal is part of Mölnlycke Health Care’s Avance® system and allows you to secure any wound with confidence – forming a seal that prevents exudate from spreading. This self-curing wound sealant uses the Safetac® technology, which means less pain for the patient.1

Perfect wherever additional fixation and sealing properties are needed

Flexible use with Avance or any other NPWT system

Easy to use

Introduction to Mepiseal

Flexible, easy-to-use wound sealant for more effective NPWT

The Mepiseal single-use applicator is simple, fast and easy to use. Once Mepiseal is activated, it will remain fluid and ready to use for 5 minutes, then it will cure.

1. Dry skin
Ensure the skin is thoroughly dry before applying Mepiseal.
2. Place the wound-filler
Place the foam or gauze dressing in the wound. If using a drain, follow the Avance instructions for use.
3. Activate Mepiseal
Twist the green cap anti-clockwise.
4. Position Mepiseal
Press the plunger to apply Mepiseal. Allow a minimum 5 mm of space from the wound margin. Apply approx. 1 cm wide and 2–5 mm thick. You can also spread Mepiseal using the tip of the applicator.
5. Apply the film dressing
Apply the film dressing immediately on top of the wound dressing and Mepiseal onto the surrounding skin.
6. Apply the NPWT
Apply the negative pressure according to the instructions for using Avance.
  1. White R. A Multinational survey of the assessment of pain when removing dressings. Wounds UK 2008; Vol 4, No 1.
  2. White R. Evidence for atraumatic soft silicone wound dressing use. Wounds UK 2005;1(3):104-9.
  3. Dykes PJ et al. Effect of adhesive dressings on the stratum corneum of the skin. Journal of Wound Care 2001;10(2):7-10.
  4. Meaume S et al. A study to compare a new self adherent soft silicone dressing with a self adherent polymer dressing in stage II pressure ulcers. Ostomy Wound Management 2003;49(9):44-51.
  5. Brindle T et al. Use of a novel injectable silicone dressing to improve outcomes with NPWT for complex wounds: a VCU experience. Poster presented at SAWC, CA, USA September 2010.
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